LABORATORY SAFETY MANUAL

SECTION I 

1. Introduction
2. Scope
3. Responsibilities
4. Raising Safety Concerns

SECTION II

1. Chemical Hygiene and Safety Plan
        a.     General Standard Operating Procedures       
2. Laboratory Housekeeping
3. Training Requirements
4. Hazardous Chemicals
5. Warning Labels
6. Material Safety Data Sheets
7. Toxicology Overview
  a. Chemical Toxicity
  b. Dose Response Relationships
  c. Route of Entry
  d. Health Effects
  e. Other Factors Affecting Toxicity
8. Prior Approval
9. Experiment Protocol Form
10. Working in Laboratories After Regular Hours
11. Unattended Experiment Policy
12. Laboratory Security Policy

SECTION III

1. Personal Protective Equipment and Clothing
  a. General Policy
  b. Eye and Face Protection
  c. Skin Protection
  d. Respirators
  e. Personal Protective Equipment (PPE) Hazard Assessment
  f. Seclection Chart for Eye and Face Protection
2. Laboratory Fume Hoods

SECTION IV

1. Fire Emergencies
2. Chemical Spills
3. Personal Contamination        
  a. General Information
  b. Chemicals Spilled on the Skin
  c. Chemicals in the Eyes
4. Accident Reporting
  a. Reporting Hazards
  b. Hazardous Substance Exposure
  c. Employee Accidents/Hazardous Substance Exposures
  d. Student Accidents/Hazardous Substance Exposures
  e. Reporting of "Near Miss" Accidents

SECTION V

1. Purchases, Donations and Transfers of Hazardous Materials
2. Purchase and Disposal of Controlled Substances
3. Chemical Storage and Transportation
  a. General Considerations for Chemical Storage
  b. Flammable and Combustible Liquid Storage
  c. Chemical Stability
  d. Shock Sensitive Chemicals
  e. Compounds that form Peroxides during Storage
  f. Compressed Gas Storage
  g. Transportation of Hazardous Chemicals

SECTION VI

1. Waste Disposal
       a.     Introduction
       b.     Responsibilities
       c.     Packaging and Labeling Procedures
       d.     Waste Reduction
       e.     Definitions
2. Chemical/Hazardous Waste Checklist for Compliance
3. Laboratory Cleanout

SECTION VII

1. Safe Handling of Flammables
2. Safe Handling of Reactive and Peroxide Forming Chemicals
3. Safe Handling of Corrosive Chemicals
4. Safe Handling of Compressed Gases
5. Safe Handling of Nanomaterials
6. Standard Operating Procedures for Reproductive Hazards, Carcinogens, or Acutely Toxic Chemicals
7. Standard Operating Procedures for Hydrofluoric Acid
8. Standard Operating Procedures for Piranha Solutions

APPENDIX

1.List of Some Carcinogens and Suspect Carcinogens
2. List of Some Reproductive Hazards
3. List of Some Acutely Toxic Chemicals
4. Examples of Incompatible Chemicals
5. Compounds That Form Peroxide During Storage


University of the Sciences in Philadelphia • 600 South Forty-third Street • Philadelphia, PA 19104-4495 • phone: 215-596-8800 • email: safety@usp.edu