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Faculty Research Interests
A bulleted listing of the research interests of all faculty members affiliated
with the Department can be found below (alphabetically by faculty name),
including Research Professors from other departments, as well as active
Emeritus faculty.
A more detailed description of any individual faculty member's research
activities (including representative publications) is available through
the link provided with each name.
Faculty with a (‡) after their name may serve as a research advisor for
undergraduates enrolled in Undergraduate Research (CH 450) and graduate
students enrolled in any of the Department's MS or PhD
Graduate Programs.
Faculty from other departments with an (*) after their name are designated
as Research Professors in the Department's Graduate Program, and may serve as
research advisors for graduate students in their appropriate area of expertise.
However, a Research Professor may NOT serve as an advisor for an undergraduate
student enrolled in Undergraduate Research (CH 450).
All other Department faculty listed may serve as a research advisor for
undergraduate students.
The "Emeritus" faculty listed are available
for consultation, but may not serve as research advisors for new graduate
students.
Adeboye Adejare, PhD*
- chemistry of fluoroaromatic compounds
- drug targeting
- mechanisms of neurodegeneration
- pharmaceutical profiling
Catherine M. Bentzley, PhD
- Analysis of polycyclic aromatic hydrocarbons and oligonucleotides
using matrix-assisted laser desorption ionization mass spectrometry
- Investigation of noncovalent interactions, for example-the process
of peptides/proteins complexing with DNA via Electrospray Ionization
(ESI)
- The rates of enzymatic reactions, such as the digestion of peptides
with carboxypeptidase Y, using MALDI and ESI
Edward R. Birnbaum, PhD
- Calcium-binding protein and peptides
- The use of lanthanide ion luminescence to probe the structure
of materials such as zeolites and high temperature superconductors
- Spectroscopic properties and coordinating chemistry of the lanthanide
ions
Michael F. Bruist, PhD
- The chemistry of DNA recombination reactions
- Protein-DNA interactions in site-specific recombination
- Local DNA strand alignment in the lambda integration reaction
- DNA isomerizations that occur during recombination
Ara DerMarderosian, PhD*
- Isolation and identification of bioactive substances from natural
products
- Phytochemical evaluation of ethnobotanicals
- Analytical evaluation of nutraceuticals
Elisabetta Fasella, PhD
- Bioorganic Chemistry
- Synthesis of enzyme inhibitors
Alfonso R. Gennaro, PhD (Emeritus)
- Analysis of drug dosage forms
- Design of drugs using structure - activity relationships
Peter J. Harvison, PhD*
- In vitro and in vivo metabolism of drugs and chemicals
- Formation and disposition of toxic metabolites
- Structure-toxicity relationships
- Application of analytical techniques such as HPLC to metabolism
studies
Joel M. Kauffman, PhD (Emeritus)
- UV-absorbing dyes for protective eyewear
- Photostable stains for biological uses
- Scintillation fluors and shifters for polystyrene fibers
- Quinolone antimicrobial drugs
Yumee K. Koo, PhD
- Protein interactions
- Chemical education
Madhu Mahalingam, PhD
- Chemical education
- Mass spectrometry
- Ion-molecule reactions
James R. McKee, PhD
- Synthesis of isonitrile antibiotics
- Chemistry of organohalogens
Preston B. Moore, PhD
- Molecular Interactions within Biological Systems
- Computational Chemistry
- Molecular Dynamics Simulations
Guillermo Moyna, PhD
- Development of methodologies for the determination of structure,
conformational preferences, and dynamics of bio-organic molecules
using NMR spectroscopy
- Study of the molecular basis of action of microtubule stabilizing
alkaloids
- Rational design of simple drugs against endemic parasitic diseases
John G. Nikelly, PhD
- Analysis of pharmaceuticals by HPLC and capillary gas column
chromatography
- Separations of chiral drugs
- Use of parallel capillary columns in gas chromatography
Vojislava Torbica-Pophristic, PhD
- Molecular Interactions within Biological Systems
- Computational Chemistry
- Inorganic Clusters
John R. Porter, PhD*
- Production strategies for medicinal natural products through
root cultures initiated by Agrobacterium rhizogenes inoculation
- Genome characterization of the plasmids of Agrobacterium
rhizogenes for understanding of the plant-microbe interactions
- Isolation and characterization of naturally-occurring cytotoxins
and antimicrobial (antibacterial, antifungal), compounds
Frederick T. Schaefer, PhD
- Chemical education
- Computer interfacing
- Macromolecules
Julian W. Snow, PhD
- Thermodynamic properties of drug - red blood cell membrane interactions
- Thermodynamic properties of the interactions between serum apolipoproteins
or model amphipathic helices with model lipid systems
Charles J. Thoman, PhD (Emeritus)
- Ionophoric properties of polysorbate 80
- The synthesis of potential anticancer and antiviral agents
- Syndone and sydnene synthesis
C. Reynold Verret, PhD
- Cell-mediated cell cytotoxicity
- Biosensors
- Peptide-based vaccines
Rodney J. Wigent, PhD
- Thermodynamic properties of drug excipients
- Effect of water content on drug release
- Physical and thermodynamic properties of aqueous electrolyte
solutions
- Environmental factors affecting DNA supercoiling
Murray Zanger, PhD (Emeritus)
- New synthetic approaches to anti-cancer drugs and anti-AIDS
drugs
- Organic reaction mechanisms
- NMR analysis of biological and pharmaceutical systems
Randy Zauhar, PhD
- Design of inhibitors against HIV protease and other polymorphic
targets
- Development of computational methods to determine solvation
effects in biological molecules
- Computer-aided drug design
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