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Pharmaceutical Chemistry
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Pharmaceutical Chemistry is an area of chemistry focused on the development, production, and delivery of drugs used to prevent, cure, and relieve symptoms of disease. Pharmaceutical chemists may synthesize new drugs, or modify older drugs so that they have improved therapeutic value, are less toxic, or have improved stability. The need to demonstrate safety, bioavailability, and effectiveness of all new drugs, as mandated by the FDA, places unique quality control requirements on all aspects of the drug manufacturing and distribution process. To meet these requirements, pharmaceutical chemists also develop improved analytical techniques for monitoring the levels of drugs in the body and to ascertain the safety and potency of the drugs on the pharmacy shelf.

Faculty with a focus in Pharmaceutical Chemistry include the following (explanation of the symbols, *, §, ‡ are listed below):

Catherine M. Bentzley, Ph.D.

Mass spectrometry of biological molecules

Ara DerMarderosian, Ph.D. *

Pharmacognosy

Medicinal chemistry

Nutraceuticals

Alfonso R. Gennaro (Emeritus), Ph.D.

Analytical drug detection development

Drug interactions

Free radical initiation of drug decomposition

John G. Nikelly, Ph.D.

The use of parallel columns in gas chromatography

Pharmaceutical analysis by GC and HPLC

Indirect detection of UV-transparent compounds

Rodney J. Wigent, Ph.D.

Solution calorimetry and thermodynamics

Thermodynamics and kinetics of drug excipients

Biophysical chemistry of DNA topology/structure

Murray Zanger (Emeritus), Ph.D.

Organic syntheses

Medicinal chemistry

Proton NMR

Research Advising Ability
§ May serve as a research advisor for undergraduate students
* Research Professors from other departments who may serve as research advisors for graduate students in their appropriate area of expertise
May serve as a research advisor for both undergraduate and graduate students

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