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Medicinal Chemistry
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Medicinal Chemistry involves the study of all compounds that may have a beneficial effect on living organisms. The discipline can be divided into several overlapping areas, including; how drugs act (mechanism of action); the design of new drugs and the improvement of known ones; the relationship of drug structure to drug activity (Structure-Activity Relationships, or SAR); and the absorption, distribution and metabolism of drugs. Medicinal Chemistry requires an extensive background in organic chemistry, but other areas of chemistry are also important (e.g., biochemistry, and analytical chemistry), as well as related disciplines outside of chemistry, such as pharmacology.

Faculty with a focus in Medicinal Chemistry include the following (explanation of the symbols, *, §, ‡ are listed below):

Adeboye Adejare, Ph.D. *

Drug targeting

Mechanisms of neurodegeneration

Chemistry of fluoroaromatic compounds

Pharmaceutical profiling

Ara DerMarderosian, Ph.D. *

Pharmacognosy

Medicinal chemistry

Nutraceuticals

Elisabetta Fasella, Ph.D. §

Bioorganic chemistry

Enzyme catalysis

Alfonso R. Gennaro (Emeritus), Ph.D.

Analytical drug detection development

Drug interactions

Free radical initiation of drug decomposition

Peter J. Harvison, Ph.D. *

Drug metabolism

HPLC method development

Structure activity/toxicity relationships

Guillermo Moyna, Ph.D.

Biomolecular NMR spectroscopy

Computational chemistry

Computer-assisted rational drug design

Murray Zanger (Emeritus), Ph.D.

Organic syntheses

Medicinal chemistry

Proton NMR

Randy J. Zauhar, Ph.D.

Computational chemistry

Bioinformatics

Computer-aided drug design

Research Advising Ability
§ May serve as a research advisor for undergraduate students
* Research Professors from other departments who may serve as research advisors for graduate students in their appropriate area of expertise
May serve as a research advisor for both undergraduate and graduate students

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