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Margaret R. Kasschau, Ph.D.
Associate Vice President for Academic Affairs
Professor, Department of Biological Sciences
PhD, Biology
University of South Carolina, 1973
(215) 596-7558
Email:m.kassch@usp.edu
Research Interests
- Osmotic effects on cell morphology and the cytoskeleton
- Relationship of these effects to heat shock proteins, protein
kinase C and p38 kinase.
Research Summary
Dr. Kasschau’s current research is involved in the study of
shape changes induced in mammalian cells and earthworm coelomocytes
subjected to osmotic stress. The relationships between environmental
high osmotic stress, cytoskeletal change, heat shock proteins, and
p38 kinase are under investigation.
Representative Publications
‡ Undergraduate Student
* Graduate Student
Kasschau, M.R., T.D.Ngo‡, L.M.Sperber‡ and K.L. Tran‡
(2007) Formation of filopodia in earthworm (Lumbricus terrestris)
coelomocytes in response to osmotic stress. Zoology (110: 66-76).
Reinhart, M., N. Dollahon, M. Kasschau (2002) Invertebrate immune
responses to eukaryotic parasites: Reaction of coelomocytes of Lumbricus
terrestris to native and non-native parasites. In A New Model
of Analyzing Antimicrobial Peptides with Biomedical Applications.
E.L. Cooper et al. (Eds), IOS Press: Amsterdam. pp. 167-173.
Kasschau, M.R., G.A. Barabino, K.R. Bridges, and D.E. Golan (1996)
Adhesion of sickle neutrophils and erythrocytes to fibronectin.
Blood 87: 771-780.
Kasschau, M.R., M.P. Byam-Smith, D.S. Gentry and F.N. Watson‡
(1995) The influence of pH and temperature on hemolysis by adult
Schistosoma mansoni membranes. J. Experim. Zool. 271: 315-322.
Representative Presentations
Patel, P., M. Dutt, M.R. Kasschau, and S.K. Murphy. Effect of P38
MAPK on filopodial formation in KG1a human hematopoietic cell line.
Poster presented at the American Society for Cell Biology Meeting
in Washington, DC, December 2007.
Dutt, M*., M.R. Kasschau, and S.K. Murphy. Role of HSP70 and the
cytoskeleton in podial formation in a human hematopoitic cell line
under hyperosmotic stress. Poster presented at the American Society
for Cell Biology meeting in San Diego, CA, December 2006.
Khanna, A.*, S.K. Murphy and M.R. Kasschau. Cytoskeletal reorganization
in a kidney cell line (LLC-PK1) under hypertonic stress. Poster
presentation at the American Society for Cell Biology meeting in
San Diego, CA, December 2006.
Dutt, M.* M.R. Kasschau, S.K. Murphy. Filopodia formation in the
KG1a human hematopoietic cell line and earthworm coelomocytes under
hypertonic stress. Poster presented at the American Society for
Cell Biology meeting in San Francisco, CA, December 2005.
Ngo, T.‡, and M.R. Kasschau. Formation and inhibition of
filopodia in earthworm coelomocytes. Poster presented at the American
Society for Cell Biology meeting in Washington, DC, December 2004.
Kasschau, M.R., L.M. Sperber‡, K. Tran, and T. Ngo‡.
Formation of filopodia in earthworm coelomocytes in response to
high osmotic stress. Poster presented at the Gordon Research Conference
on Cellular Osmoregulation in Bristol, RI, August 2003.
Created by: Robert A. Smith
Last updated: January 2008
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