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Jennifer R. Anthony
Assistant Professor of Biology
Office: STC 277
Phone: (215) 596-7437
Email: j.anthon@usip.edu
Training
Post-Doctoral Fellowship, University of California, Berkeley (2005-2007)
Ph.D. Microbiology, University of Wisconsin-Madison (2005)
B.S. Biology, University of Wisconsin-LaCrosse (1998)
Research Interests
Terpenoids comprise the largest and most diverse family of natural
products. They are a rich source of therapeutic and commercially
useful compounds. The Anthony lab focuses on production of terpenoids
in E. coli. Our interest lies in characterizing the enzymes that
catalyze synthesis of these compounds, and in optimizing these enzymes
for high-level production in E. coli. Another focus of our lab is
characterizing the physiological consequences of expressing these
heterologous pathways in E. coli.
Selected Publications
Anthony, J.R., Anthony, L.C., Nowroozi, F., Kwon, G., Newman, J.D.,
and J.D. Keasling. 2007. A modular approach to improving metabolic
pathways: application to production of the anti-malarial drug precursor
amorpha-4,11-diene in Escherichia coli. Metab. Eng. (Submitted).
Campbell, E.A., Greenwell, R., Anthony, J.R., Wang, S., Lim, L.,
Das, K., Sofia, H.J., Donohue, T.J., and S.A. Darst. 2007. A conserved
structural module regulates transcriptional responses to diverse
stress signals in bacteria. Mol. Cell. 27: 793-805.
Anthony, J.R., Warczak, K.L., and T.J. Donohue. 2005. A transcriptional
response to a toxic byproduct of photosynthesis. PNAS. 102: 6502-6507.
Teaching Responsibilities
BS348 – Clinical Microbiology
BS453 – Microbial Physiology
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