Mary Beth Murray
Mary Beth Murray
Assistant Professor of Biology
Department of Biological Sciences
Contact Info:
Office: STC 344
McNeil Science & Technology Center
Voice: (215) 596-7436
Fax: (215) 596-8710
Email: m.murray@usp.edu
Training and Degrees
Ph.D., Biochemistry, University of Minnesota, Minneapolis, MN, 1989
B.S., Biology, University of Minnesota, St. Paul, MN, 1982
Prior Positions
Adjunct Faculty, Drexel University, Phila., PA 2000-2004
Part-time Faculty, Community College of Phila., 2004
Postdoctoral Fellow, Univ. of Tennessee-Oak Ridge Graduate School of Biomedical Sciences and Oak Ridge National Laboratory, 1994-1998
Research Associate/Postdoctoral Fellow, Johns Hopkins University School of Medicine, Baltimore, MD, 1989-1994
Research Assistant, University of Minnesota Medical School, Minneapolis, MN, 1984-89
Laboratory Attendant, University of Minnesota, St. Paul, MN 1983-84
Research Interests
Development of a yeast model system to study adenosine deaminase-adenosine receptor interactions.
Selected Recent Publications
Murray, M. B., Tadaki, D. T., Campion, S. A., Lamerdin, J. A., Serpersu, E. H., Bradrick, T. D., and Niyogi, S. K. (1998) “Structure-function Analysis of a Conserved Aromatic Cluster in the N-terminal Domain of Human Epidermal Growth Factor.” Protein Engineering 11, 1041-1050.
Neelam, B., Richter, A., Chamberlin, S. G., Puddicombe, S. M., Wood, L., Murray, M. B., Nandagopal, K., Niyogi, S. K., and Davies, D. E. (1998) “Structure-function Studies of Ligand-induced Epidermal Growth Factor Receptor Dimerization,” Biochemistry 37, 4884-4891.
Zilz, N. D., Murray, M. B., and Towle, H. C. (1990) “Identification of Multiple Thyroid Hormone Response Elements Located Far Upstream from the Rat S14 Promoter.” J. Biol. Chem. 265, 8136-8143.
Niyogi, S. K., Nandagopal, K., Murray, M. B., Puddicombe, S. M., Richter, A.,
Davies, D. E., Reddy, C. C., and Lauffenburger, D. A. (1998) “Use of Engineered Variants of Human Epidermal Growth Factor (hEGF) in Elucidating Growth Signaling.” ,em>FASEB J. 12, A1342.
Puddicombe, S. M., Richter, A., Chamberlin, S. G., Murray, M. B., Wood, L., Nandagopal, K., Niyogi, S. K., and Davies, D. E. “Evidence for Selective Heterodimerization of the Epidermal Growth Factor Receptor (EGFR) by Site Mutants of EGF.” Modes of EGF Receptor Signaling, Ames, IA, Sept. 25-28, 1997.
Richter, A., Neelam, B., Chamberlin, S. G., Puddicombe, S. M., Murray M. B., Nandagopal, K., Niyogi, S. K., and Davies, D. E. “Structure-function Studies of Ligand-induced Epidermal Growth Factor Receptor Dimerization.” Modes of EGF Receptor Signaling, Ames, IA, Sept. 25-28, 1997.
Murray, M. B. and Niyogi, S. K. “A Role for Leucine 47 of Human Epidermal Growth Factor in Receptor Dimerization and Activation.” Cellular Regulation by Protein Phosphorylation: Forty Years of Progress, Seattle, WA, Aug. 20-23, 1997.
Murray, M. B., Lamerdin, J. A., Nandagopal, K., Niyogi, S. K., and Serpersu, E. H. (1996) “1H-NMR pH Titration Analysis of the Aromatic Side-chains of Human Epidermal Growth Factor (hEGF).” FASEB J. 10, A1400.
Murray, M. B. and Towle, H. C. (1989) “Identification of Nuclear Factors that Enhance Binding of the Thyroid Hormone Receptor to a Thyroid Hormone Response Element.” Mol. Endocrinol. 3, 1434-1442.
Murray, M. B., Zilz, N. D., McCreary, N. L., MacDonald, M. J., and Towle, H. C. (1988) “Isolation and Characterization of Rat cDNA clones for Two Distinct Thyroid Hormone Receptors.” J. Biol. Chem. 263, 12770-12777.