Margaret R. Kasschau, PhD
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Margaret R. Kasschau, Ph.D.
Associate Provost & Professor Emeritus
Department of Biological Sciences
Contact Info:
Office: WH 2300
Whitecar Building
Voice: (215) 596-7558
Fax: (215) 596-8544
Email: m.kassch@usp.edu
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Training and Degrees
PhD, Biology University of South Carolina 1973
MS, Biology, University of South Carolina 1970
BA, Biology, University of Rochester 1964
Prior Positions
Assistant, Associate, Professor of Biology, University of Houston Clear Lake, 1975-1994
Chair, Biological Sciences, University of the Sciences in Phila., 1994-2004
Membership in Professional Organizations
American Society for Cell Biology
Biophysical Society, AAAS, Association for Women in Science
Research Interests
Osmotic effect on cell morphology and the cytoskeleton. Relationship to heat shock proteins, protein kinase C and P38.
Selected Recent Publications and Presentations
‡ Undergraduate Student
* Graduate Student
Patel, P.*, H. Tyagi, A. Khanna*, M. Kasschau, and S. Murphy, “Role of P38MAPK and Heat Shock Proteins HSP27 and HSP70 in osmotic stress in renal vs. blood cells; comparative study. Poster presented at the American Society for Cell Biology meeting in San Francisco, CA, Dec. 2008.
Kasschau, M.R., T.D.Ngo‡, L.M.Sperber‡ and K.L. Tran‡ (2007) Formation of filopodia in earthworm (Lumbricus terrestris) coelomocytes in response to osmotic stress. Zoology (Jena), 110: 66-76.
Patel, P.*, M. Dutt*, M.R. Kasschau, S.K. Murphy, “Effect of P38MAPK on filopodial formation in KG1 a human hematopoietic cell line. Poster presentation at the American Society for Cell Biology meeting in Washington, DC, December 2007.
Dutt, M*., M.R. Kasschau, and S.K. Murphy. Role of HSP70 and the cytoskeleton in podial formation in a human hematopoitic cell line under hyperosmotic stress. Poster presented at the American Society for Cell Biology meeting in San Diego, CA, December 2006.
Khanna, A.*, S.K. Murphy and M.R. Kasschau. Cytoskeletal reorganization in a kidney cell line (LLC-PK1) under hypertonic stress. Poster presentation at the American Society for Cell Biology meeting in San Diego, CA, December 2006.
Dutt, M.* M.R. Kasschau and S.K. Murphy. Filopodia formation in the KG1a human hematopoitic cell line and earthworm coelomocytes under hypertonic stress. Poster presented at the American Society for Cell Biology meeting in San Francisco, CA, December 2005.
Ngo, T.‡, and M.R. Kasschau. Formation and inhibition of filopodia in earthworm coelomocytes. Poster presented at the American Society for Cell Biology meeting in Washington, DC, December 2004.
Kasschau, M.R., L.M. Sperber‡, K. Tran, and T. Ngo‡. Formation of filopodia in earthworm coelomocytes in response to high osmotic stress. Poster presented at the Gordon Research Conference on Cellular Osmoregulation in Bristol, RI, August 2003.
Reinhart, M., N. Dollahon and M. Kasschau (2002) Invertebrate immune responses to eukaryotic parasites: Reaction of coelomocytes of Lumbricus terrestris to native and non-native parasites. In A New Model of Analyzing Antimicrobial Peptides with Biomedical Applications. E.L. Cooper et al. (Eds), IOS Press: Amsterdam. pp. 167-173.
Kasschau, M.R., G.A. Barabino, K.R. Bridges, and D.E. Golan (1996) Adhesion of sickle neutrophils and erythrocytes to fibronectin. Blood 87: 771-780.
Kasschau, M.R., M.P. Byam-Smith, D.S. Gentry and F.N. Watson‡ (1995) The influence of pH and temperature on hemolysis by adult Schistosoma mansoni membranes. J. Experim. Zool. 271: 315-322.