Jennifer R. Anthony
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Jennifer R. Anthony
Assistant Professor of Biology
Contact Info:
Office: STC 277
McNeil Science & Technology Center
Voice: (215) 596-7437
Fax: (215) 596-8710
Email: j.anthon@usp.edu
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Training and Degrees
Post-Doctoral Fellowship, University of California, Berkeley (2005-2007)
Ph.D. Microbiology, University of Wisconsin-Madison (2005)
B.S. Biology, University of Wisconsin-LaCrosse (1998)
Prior Positions
Graduate Fellow, University of Wisconsin-Madison, January 2000-April 2005
Identification of a physiological role for the Rhodobacter sphaeroides sigma factor, RpoE.
Research Technician, University of Wisconsin-Madison, June 1998-September 1999
In vitro and in vivo activation of the anaerobically-induced promoter, cycAP2, by the photosynthetic response regulator PrrA of Rhodobacter sphaeroides
Membership in Professional Organizations
American Association for the Advancement of Science
American Society of Microbiology
Research Interests
Metabolic engineering of Escherichia coli for the production of terpenoids. Optimization of protein expression and enzyme activity for multi-gene pathways. Characterization of the physiological consequences of expressing heterologous pathways in E. coli.
Selected Recent Publications
Anthony, J.R., Anthony, L.C., Nowroozi, F., Kwon, G., Newman, J.D., and J.D. Keasling. 2008. A modular approach to improving metabolic pathways: application to production of the anti-malarial drug precursor amorpha-4,11-diene in Escherichia coli. Metab. Eng. (In Press).
Campbell, E.A., Greenwell R., Anthony, J.R., Wang, S., Lim, L., Das, K., Sofia, H.J., Donohue, T.J., and S.A. Darst. 2007. A conserved structural module regulates transcriptional responses to diverse stress signals in bacterial. Mol Cell. 27:793-805.
Anthony, J.R., Warczak, K.L., and T.J. Donohue. 2005. A transcriptional response to a toxic byproduct of photosynthesis. PNAS. 102:6502-6507.
Anthony, J.R., Newman, J., and T.J. Donohue. 2004. Interactions between the Rhodobacter sphaeroides ECF sigma factor, sE, and its anti-sigma factor, ChrR. J Mol Biol. 341:345-360.
Anthony, J.R., Green, H., Newman, J., and T.J. Donohue. 2003. Purification of Rhodobacter sphaeroides RNA polymerase and its sigma factors. Methods Enzymol. 370:54-65.
Newman, J.D., Anthony, J.R., and T.J. Donohue. 2001. The importance of zinc-binding to the function of Rhodobacter sphaeroides ChrR as an anti-sigma factor. J Mol Biol. 313:485-499.
Hirvonen, C.A., Ross, W., Wozniak, C.E., Marasco, E., Anthony, J.R., Aiyar, S.E., Newburn, V.H., and R.L. Gourse. 2001. Contributions of UP elements and the transcriptional factor FIS to expression from the seven rrn P1 promoters in Escherichia coli. J Bacteriol. 183:6305-6314.
Karls, R.K., Wolf, J.R., and T.J. Donohue. 1999. Activation of the cycA P2 promoter for the Rhodobacter sphaeroides cytochrome c2 gene by the photosynthesis response regulator. Mol Microbiol. 34:822-835.